Nerve Block in the Pre-Operative (Pre-Op) vs. Operative Room (OR)
Peripheral nerve blocks offer targeted analgesia, reduced opioid use, and improved postoperative outcomes when incorporated into multimodal analgesic care compared with systemic analgesics alone. While the efficacy of nerve blocks for pain control is well established, debate persists regarding the optimal timing and location for administration—specifically, whether a nerve block should be placed in a pre-operative (pre-op) area or within the operating room (OR).
One of the principal arguments for performing the nerve block in the pre-op room is enhanced OR efficiency. Traditional workflows have the block placed after the patient enters the OR, which counts in surgical block time. Designating a separate space for nerve block performance enables parallel processing, which allows anesthesiologists to administer blocks while other cases are finishing and designates OR time only for the surgery itself. Implementation of dedicated block rooms has been associated with meaningful reductions in anesthesia control time and improved throughput in high-volume orthopedic settings.
Safety considerations also support the pre-op model when structured protocols are used. Standardized workflows incorporating checklists, time-outs, ultrasound guidance, and documentation protocols have been shown to improve compliance with safety standards for peripheral nerve blocks performed outside the OR. Performing the block prior to transport to the OR also allows the anesthesia team to assess block onset, dermatomal spread, and adequacy under less time pressure, potentially decreasing the need for rescue analgesia intraoperatively.
However, in certain situations, administering the nerve block in the OR demonstrates clear benefits. Logistically, surgical schedules may not be predictable enough to time the block for an upcoming case while the previous case is ongoing. In addition, staffing models or space constraints may not support a dedicated block area. Performing the nerve block in the OR rather than the pre-op room is necessary when anesthesia induction occurs first, as may be the case when trying to improve patient comfort in anxious individuals or in circumstances where positioning would be uncomfortable while awake.
Performing the peripheral nerve block in a dedicated pre-op area before the patient enters the OR can enhance workflow efficiency and reduce anesthesia control time. The success of this model depends on appropriate staffing, standardized safety protocols, and institutional support.
References
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2. Polshin V, Petro J, Wachtendorf LJ, et al. Effect of peripheral nerve blocks on postanesthesia care unit length of stay in patients undergoing ambulatory surgery. Reg Anesth Pain Med. 2021;46(3):233-239. doi:10.1136/rapm-2020-102231
3. Starr A, Joshi GP. Comparison of regional anesthesia timing on pain, opioid use, and PACU length of stay in patients undergoing open reduction and internal fixation of ankle fractures. J Foot Ankle Surg. 2020;59(4):788-791. doi:10.1053/j.jfas.2019.05.012
4. Arbizo JC, Dalal K, Lao V, et al. Safe preoperative regional nerve blocks. BMJ Open Qual. 2022;11(1):e001370. doi:10.1136/bmjoq-2021-001370
5. Acar MS, Pehlivan VF, Pehlivan B, Duran E. Timing matters: a randomized controlled trial comparing preoperative and postoperative erector spinae plane block for analgesia in laparoscopic cholecystectomy. Medicina (Kaunas). 2025;61(10):1806. doi:10.3390/medicina61101806
